Print the page
Increase font size
Red Turns to Green

Posted September 22, 2021

Aaron Gentzler

By Aaron Gentzler

Red Turns to Green

“Monday was an ugly day in the markets, no doubt about that,” says our science and technology authority Ray Blanco.

“We had the Dow down over 600 points, the Nasdaq down over 2%, and the S&P not much better.

“But I think it’s always important to point out the silver linings of these situations,” he says.

“When you have a deep red day like we saw Monday, there are almost always pockets of green to be found. And usually, those outperformers are biotech stocks.

“Even on days when the market is going through a broad correction, you can still make a lot of money trading biotech companies working on cutting-edge technologies. Especially if there is a bullish catalyst involved…

Send your opinions to, TheRundownFeedback@StPaulResearch.com

Your Rundown for Wednesday, September 22, 2021...

Novel Therapy Initiates Immune Response

“One company I’d like to talk about in particular is Innate Pharmaceuticals (IPHA),” says Ray.

“Innate is working on a cutting-edge platform that uses your own killer immune system cells, cells that are part of your innate immune system.

“Our immune systems are made up of two parts, the adaptive immune system, and the innate immune system.

“Your adaptive immune system works when it’s engaged, for example, by a vaccine. When you get a vaccine, your immune system adapts to the antigens in it,” Ray explains. “Then, if you are exposed to the pathogen, your immune system is already adapted to it. Allowing your body to fight the pathogen off more effectively.

“Your innate immune system, however, is there as a first response to any unusual activity going on in the body, like cancer cells. And this is exactly what Innate Pharmaceuticals is working on.

“Research has shown that there is a relation between the immune system and cancer treatment -- we just didn’t really know how to engage the immune system's help until recently.

“Medical technology already has cancer treatment platforms based on the adaptive immune system, but Innate Pharmaceuticals is working on a platform that utilizes your innate immune system.

“They have a plethora of therapies. Most of which are antibody therapies that work in various ways when responding to cancer cells,” Ray says. “And in early September, they announced that they will be presenting at the European Society for Medical Oncology.

“So far, their data has shown strong promise in their therapies' ability to combat cancer cells. They also have partnerships with the bigger pharmaceutical companies to help facilitate their research.

“Last, the stock has finally entered an uptrend breakout after a sleepy start earlier this year.

“All this to say IPHA is a small speculative biotech play,” Ray cautions. “It can move big, up and down, on data. So keep that in mind if you plan on trading this company.”

Market Rundown for Wednesday, Sept. 22, 2021

S&P 500 futures are up 25 points to 4,370.

Oil is up 87 cents to $71.36 for a barrel of WTI.

Gold’s down $4.20 to $1,774.10 per ounce.

Bitcoin is up $70 to $42,185 at the time of writing.

Send your comments and questions to, TheRundownFeedback@StPaulResearch.com

Have a great rest of your day… Check back Friday.

For The Rundown,

Aaron Gentzler

Aaron Gentzler
Editor, The Rundown
TheRundownFeedback@StPaulResearch.com

Flynt & Falwell Outclass Mamdani

Flynt & Falwell Outclass Mamdani

Posted January 16, 2026

By Matt Insley

On January 1, New York City’s new mayor, Zohran Mamdani, delivered an inauguration speech that was instantly celebrated. But one sentence deserves scrutiny
Trump Owns Democrats Again

Trump Owns Democrats Again

Posted January 14, 2026

By Matt Insley

President Trump has waved off Democrats’ talk of “affordability” as political theater. This January, he’s doing the opposite: owning the issue.
California Killed the Middle Class

California Killed the Middle Class

Posted January 12, 2026

By Matt Insley

California is an isolated fuel market. When supply tightens there, it doesn’t snap back easily.
Nvidia Haters Are Seething

Nvidia Haters Are Seething

Posted January 09, 2026

By Matt Insley

Shorts got run over, and Jensen has big plans to continue the boom...
Okay, I Get Why Robots Have Two Legs

Okay, I Get Why Robots Have Two Legs

Posted January 07, 2026

By Matt Insley

This week at the Consumer Electronics Show in Las Vegas, the most important reveal wasn’t a device or a screen. It was a worker.
Buck Sexton on Venezuela

Buck Sexton on Venezuela

Posted January 05, 2026

By Matt Insley

Buck Sexton recounts how events in Venezuela went from “regional drama” to “global hotspot” quicker than most anyone expects.